What specific instruction did Jesus give the Twelve regarding their target audience during their mission?

Jesus specifically told the twelve disciples to go only to Jewish towns and people, not to Gentiles or Samaritans. This was their first mission trip, focused on Israel.

Later, after His resurrection, Jesus would send them to all nations. But at this time, His mission was primarily to the Jewish people first.

This shows that God had a specific order for spreading the good news.