The /ʃ/ sound in “sheep” is also found in:

The /ʃ/ sound in “sheep” is also found in:

  1. machine ✓
  2. chip
  3. sing
  4. jeep

Explanation

Enzyme-substrate specificity: each enzyme has active site with specific shape. Only substrates with complementary shape can bind – like lock and key. This ensures enzymes catalyze correct reactions.

Induced fit model: active site shape adjusts slightly to fit substrate. More accurate than rigid lock-and-key model. Binding causes conformational change enabling reaction.

Competitive inhibitors: similar shape to substrate, block active site. Non-competitive inhibitors: bind elsewhere, change enzyme shape. Enzyme inhibition can be therapeutic (drug target) or harmful (poison).